search-white-svg
Meine Position
i
Ein Tipp vom Eldar Team
Je mehr Sie bestellen, desto grösser Ihr Rabatt
Sofort lieferbar
Comparative Biology of Aging
Buch
Buch
disk-white-svg
Fachbuch
2010

Comparative Biology of Aging

ISBN
EAN
978-90-481-3464-9
9789048134649
Artikel-Nr.
W9GKR62
Sofort lieferbar:
1
Kostenloser Versand
Rabatt
-11.5
%
CHF 150.00
CHF
132.68
Anzahl
1
Maximale
Lieferzeit
5
Arbeitstage
Donnerstag
30.09.2021
speech-bubble-svg Beschreibung
determined by an inability to move in response to touch. C. elegans develop through four larval stages following hatching and prior to adulthood. Adult C. elegans are reproductive for about the rst week of adulthood followed by approximately two weeks of post-reproductive adulthood prior to death. Life span is most commonly measured in the laboratory by maintaining the worms on the surface of a nutrie- agar medium (Nematode Growth Medium, NGM) with E. coli OP50 as the bacterial food source (REF). Alternative culture conditions have been described in liquid media; however, these are not widely used for longevity studies. Longevity of the commonly used wild type C. elegans hermaphrodite (N2) varies ? from 16 to 23 days under standard laboratory conditions (20 C, NGM agar, E. coli OP50 food source). Life span can be increased by maintaining animals at lower ambient temperatures and shortened by raising the ambient temperature. Use of a killed bacterial food source, rather than live E. coli, increases lifespan by 2–4 days, and growth of adult animals in the absence of bacteria (axenic growth or bac- rial deprivation) increases median life span to 32–38 days [3, 23, 24]. Under both standard laboratory conditions and bacterial deprivation conditions, wild-derived C. elegans hermaphrodites exhibit longevity comparable to N2 animals [25].
Inhaltsverzeichnis
1. Introduction and end of life pathologies Norman Wolf and Steven Austad 2. Animal size, metabolic rate, and survival, among and within species Steven Austad 3. Hormonal Influences on Aging and Lifespan Adam Spong and Andrzej Bartke 4. Exploring mechanisms of aging retardation by caloric restriction: studies in model organisms and mammals. Rozalyn Anderson, Ricki Colman & Richard Weindruch 5. Cell Replication Rates In Vivo and In Vitro and Wound Healing as Affected by Animal Age, Diet, and Species. Norman Wolf 6. The Comparative Biology of Sirtuin Function in Longevity Daniel L. Smith, Jr., and Jeffrey S. Smith 7. The Role of TOR signaling in Aging. Matt Kaeberlein and Lara S. Shamieh 8. Mitochondria, Oxidative Damage and Longevity: What Can Comparative Biology Teach Us? Yun Shi, Rochelle Buffenstein and Holly Van Remmen 9. Comparative genomics of aging. Jan Vijg, Ana Maria Garcia, Brent Calder and Martijn Dollé 10. Changes in lysosomes and their autophagic function in aging. The comparative biology of lysosomal function. Samantha J. Orenstein and Ana Maria Cuervo 11. Telomeres and telomerase. Inter-species comparisons of genetic, mechanistic and functional aging changes. N.M.V. Gomes, J.W. Shay, W.E. Wright, 12. Cardiac Aging. Dao-Fu Dai, Robert J. Wessells, Rolf Bodmer, Peter S. Rabinovitch 13. Comparative Skeletal Muscle Aging. David J. Marcinek, Jonathan Wanagat, Jason J. Villarin 14. Aging of the Nervous System. Catherine A. Wolkow, Sige Zou and Mark P. Mattson 15. Aging of the Immune System across Different Species. Janko Nikolich-Zugich and Luka Cicin-Sain
feather-svg
Herausgeber/-in
Herausgegeben von
Zielgruppe
Research
Publikation
Niederlande
04.02.2010
speech-bubble-svg
Sprache
Englisch
book-svg Format
Hardcover
391 Seiten
package-svg Versand
Kostenloser Versand: Schweiz & Liechtenstein
Für den Versand nach Deutschland oder Frankreich werden die Versandgebühren der Schweizerischen Post berechnet. Diese werden Ihnen im Warenkorb für Ihre gesamte Bestellung berechnet.
subcategories-svg
Themen
Zurück
Zum Start
S
SPIEGEL Bestseller
Hauptkategorie