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Microfluidics for Single-Cell Analysis
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eBook
Fachbuch
2019

Microfluidics for Single-Cell Analysis

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Autor/-in
ISBN
EAN
978-981-3297-29-6
9789813297296
Artikel-Nr.
7L3VZGZ
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-21.8
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CHF 106.50
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83.34
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1
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This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.

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Inhaltsverzeichnis
Advances of single-cell analysis on microfluidics.- Microfluidic technology for single-cell capture and isolation.- Single cell culture and analysis on microfluidics.- Droplet microfluidic technology for single cell manipulation.- Droplet-based microfluidics for single cell encapsulation and analysis.- Microfluidics for Single-Cell Genomics.- Microfluidics-mass spectrometry combination systems for single cell analysis.- Micro/nano fluidics-enabled single-cell biochemical analysis.- Microfluidic chip based Live Single-Cell Probes.
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Biografie

Professor Jin-Ming Lin was born in 1963. He received his Bachelor of Science degree at Fuzhou University in 1984 and his PhD in analytical chemistry at Tokyo Metropolitan University, Japan in 1997. He studied and worked at Showa University, Japan and Tokyo Metropolitan University from 1992 to 2002. He was a professor at the Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences from 2002 to 2004, and has been a professor at Tsinghua University, China since 2004 and was selected as Cheung Kung Scholars Professor of Ministry of Education, China at 2008. He is a Fellow of Royal Chemical Society. He is a general secretary and deputy chair of Mass Spectrometry Committee, Chinese Chemical Society, a vice president Chinese Society of Mass Spectrometry, and a member of the council of the Chinese Society for Chromatography Science. He received several awards for his contributions in chemiluminescence and separation science: Outstanding Young Chemist Award (Chinese Chemical Society, 1992), Young Analyst Award for Flow Injection Analysis (Flow Injection Section, Japan Society of Analytical Chemistry, 2000), Kanton New Century Award (Japan Society of Analytical Chemistry, 2001), National Science Fund for Distinguished Young Scholars of China (National Natural Science Foundation of China, 2002), FIA Award for Science (Flow Injection Section, Japan Society of Analytical Chemistry, 2008), GC Contribution Award (GC Discussion Group, Japan Society of Analytical Chemistry, 2008, 2013), CAIA Awards (China Association for Instrumental Analysis, 2009, 2010 and 2015), Science and Censorship Award (General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China, 2010), Award for Science and Technology(Beijing City, 2013), Natural Science Award (Ministry of Education, China, 2015), Liang Shuquan Award for Analytical Chemistry (Chinese Chemical Society, 2015), and Silver Prize from The 10th Race Award for Innovation and Creative Patents (The Innovation Association of Beijing City, China, 2016). His current research is focused on sample pretreatment, chemiluminescence and microfluidic devices. He is the author and co-author of 388 original research papers published in international journals, 32 reviews, 4 books and 45 patents.

Publikation
Singapur
28.08.2019
Springer Verlag
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Sprache
Englisch
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eBook
PDF
261 Seiten
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