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Beschreibung
Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine or blood. The analytical methods for detection of substances in biological media have been considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and is currently used in surveillance programs all over the world. This two-volume handbook provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books describe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume 1: Ongoing Programs and Exposures describes current human biomonitoring activities in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in human exposures to lead and increasing concern related to adverse effects from exposures to endocrine disruptors and genotoxic compounds. Chapters are also included on biomarkers of specific exposures in a range of widely used everyday compounds such as phthalates, PFCs, bisphenol A, brominated flame retardants, lead, PAHs, dioxins, mercury and arsenic. Volume 2: Selected Biomarkers of Current Interest contains chapters describing human biomonitoring of exposures to environmental tobacco smoke, mycotoxins, physiological stress, hormone activity, oxidative stress and ionizing radiation, as well as chapters on exposure/early effect biomarkers such as hemoglobin adducts, germ cells, micronuclei and of individual susceptibility. The final chapter addresses ethical issues related to human sampling and monitoring.
Spezifikationen
Sprache
- Englisch
Autor
- Lisbeth Knudsen
- Domenico Franco Merlo
Erscheinungsjahr
- 2011
Format
- Buch (Hardcover)
Anzahl Seiten
- 278