General Pharmacology

1: Methods of General Pharmacology. - 2: The Cell as a Physico-chemical System. - 3: General Characteristics of the Cell-Drug System. - 4: Reactions between Drugs and Active Proteins. - 5: The Action of Drugs on Catalysts and Enzymes. - 6: Action of Heavy Metals on Enzymes in vitro and in vivo. - 7: Action of Various Enzyme Poisons in vitro and in vivo. - 8: Concentration-action Relations I. - 9: Concentration-action Relations II. - 10: Quantitative Pharmacology and the Theory of Humoral Transmission. - 11: Kinetics of Drug Action. - 12: The Rate of Action of Drugs on Cells. - 13: Time-concentrations Curves. - 14: Individual Variation of Response to Drugs. - 15: Relation between Various Types of Curves Expressing Response of Cells to Drugs. - 16: Special Problems Relating to Variation of Populations. - 17: Quantitative Aspects of Drug Antagonism and of Drug Synergism. - 18: Qualitative Aspects of Drug Antagonism. - 19: Alternative Theories of Drug Action. - 20: Quantitative Aspects of Chemotherapy. - 21: Conclusion. - Index of Authors. - Index of Subjects.