The Diabetes Textbook

Preface: A New Disease?.- The Human Burden: Epidemiology of Diabetes across the World.- The Economic Burden: Direct and Indirect Costs of Diabetes.- The Global Burden of Diabetes.- The Ecological Approach to Self-Management in Diabetes.- Diabetes Outcomes and Social Determinants of Health.- Definition, Diagnostic Criteria, Screening, Diagnosis and Classification of Diabetes and Categories of Glucose Intolerance: an Update.- Homeostasis of Glucose and Intermediate Metabolism.- Pathophysiology of Type 1 Diabetes.- Pathophysiology of Type 2 Diabetes.- Genetic Determinants of Type 2 Diabetes.- Gene Expression Modifications in Type 2 Diabetes.- The Immune System and Inflammation in Type 2 Diabetes.- Dysfunction and Death of Pancreatic Beta Cells in Type 2 Diabetes.- Obesity in the Pathophysiology of Diabetes.- Pathogenesis of Gestational Diabetes.- Non-Alcoholic Fatty Liver in the Pathogenesis of Diabetes.- Microbiota in the Pathogenesis of Diabetes.- Diabetes and Circadian Rhythms.- Diabetes Management in Europe.- Diabetes Management in Asia.- Diabetes Management in the Americas.- Diabetes Management in the United States.- Diabetes Management in Mexico.- Diabetes Management in Africa.- Diabetes Management in Australia.- Evolution of the Patient-Centered Medical Home and Diabetes Care.- Outpatient Diabetes Management and the Chronic Care Model.- Clinical Practice Guidelines and Diabetes.- Evidence-Based Medicine and Diabetes: Contribution of Trials and Mega-Trials.- Measuring Diabetes Quality of Care: Clinical Outcomes, Cost-Effectiveness, and Patient Experience of Care.- Clinical Inertia and Diabetes Outcomes.- The Continuing Challenge of Patient Adherence.- Challenges and Scope of Diabetes Self-Care Education and Support.- Diabetes and Mental Health.- Tools of Self-Care: Self-Monitoring of Blood Glucose and Tele-Health Resources.- Continuous Glucose Monitoring in Clinical Practice: Ambulatory Glucose Profile and Advanced Glucose Sensing Technologies.- Type 2 Diabetes and Lifestyle Medicine.- Evidence and Implementation of Medical Nutrition Therapy in Persons with Diabetes.- Evidence and Implementation of Physical Activity and Exercise in Diabetes Management.- The “Old” Oral Antidiabetics.- Incretin Therapies: Current Use and Emerging Possibilities.- Sodium-Glucose Cotransporter 2 Inhibitors.- Use of Insulin in Outpatient Diabetes Management.- Insulin Pump Therapy.- Diabetes and Hypertension.- Diabetes and Atherogenic Dyslipidemia.- Obesity and Diabetes.- Metabolic and Bariatric Surgery in Diabetes Management.- Diabetes and Smoking: The Burden of Evidence.- Hyperglycemic Crises: Diabetic Ketoacidosis and Hyperosmolar Non-Ketotic Status.- Hypoglycemia: Diagnosis, Management and Prevention.- Inpatient Management of Diabetes and Hyperglycemia.- Diabetes and Infection.- Biochemical Mechanisms of Vascular Complications in Diabetes.- Diabetes and Cardiovascular Disease.- Diabetes and Stroke: The Role of Glucose Regulation.- Peripheral Arterial Disease and Diabetes Mellitus.- Ophthalmic Disease in Diabetes.- Diabetes and Oral Health.- Renal Disease in Diabetes.- Peripheral Diabetic Neuropathies.- Diabetic Cardiac Autonomic Neuropathy.- Autonomic Visceral Neuropathy and Gastrointestinal Disorders.- Urologic Complications of Diabetes.- Musculoskeletal Complications of Diabetes.- Diabetes and the Skin.- Foot Complications.- Diabetes and Cancer.- Diabetes in Children and Adolescents.- Pregnancy: Pregestational and Gestational Management.- The Elderly with Diabetes.- The Artificial Pancreas.- Stem-Cell Therapy.- Immune-Regulating Interventions.- Unproven Therapies for Diabetes.- Diabetes Prevention.